Apostles Lutheran Church was established in the O'Fallon area in 2000 when the congregation started worshiping at the Knights of Columbus in Dardenne. In 2009 they built their own church at 2600 Bates Road. On Sundays they offer Bible study for all ages with an adult Bible hour, Real Life teen study and Sunday school.
On the first Saturday of every month they host "The Event," a casual service beginning with worship and ending with a meal.
Apostles Lutheran Church offers congressional sports and encourages their youth to participate in service projects. For the past two years the families of the church have hosted a run to raise money to build schools in Haiti.
Holy Cross Lutheran Church was one of the first Lutheran congregations established in O'Fallon. After moving around to several different locations, including the VFW Hall and O'Fallon Mortuary Hall, the current church on Veterans Memorial Parkway was built in May 1975.
Holy Cross Lutheran participates in several community outreach programs, including providing support for the Hope Ministry Food Pantry and working with the O'Fallon Police Chaplains to provide assistance to those in temporary need of food, gas or utilities.