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Brisbane / California / United States
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Brisbane / California / United States
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MacroGenics is a private, venture-backed biotechnology company that focuses on the discovery, development and delivery to patients of novel biologics for autoimmune disorders, cancer and infectious diseases. Since it s founding in 2000, the company has built a fully integrated set of capabilities in monoclonal antibody product development. The company s product development efforts leverage three proprietary technology platforms: (1) cancer stem-like cells; (2) Dual Affinity Re-Targeting (DART), which allows the company to incorporate multiple specificities within a single molecule; and (3) Fc optimization, which enhances antibody-dependent effector functions. These powerful sets of capabilities and technology platforms have enabled MacroGenics to build a proprietary pipeline of innovative product candidates.
Brisbane / California / United States
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XDx, also known as Expression Diagnostics, is a molecular diagnostics company that specializes in the discovery, development and commercialization of noninvasive gene expression testing. The company has expertise in the areas of transplant medicine and autoimmunity. Established in 2000, XDx has developed a proprietary method of utilizing gene expression in blood that provides a new tool for physicians to manage the care of heart transplant patients. It offers a proprietary product called AlloMap that is used in molecular expression testing. XDx maintains its headquarters in Brisbane, Calif.