Looking for a bank in Spartanburg, SC? The Spartanburg Main branch is located near the intersection of Henry Street and South Pine Street, across from the YMCA in Spartanburg County. Anywhere you find a Regions Bank office in SC, you’ll find knowledgeable professionals to help you take your next step while providing exceptional customer service and financial guidance. They can provide you with a full range of product and services to meet your financial needs, including check cashing1 and/or Western Union® money transfers. Plus with our extensive ATM network, Online Banking and Mobile Banking2, you can bank conveniently in SC or just about anywhere else. Make an appointment today to learn more.